Antigen: Feline Immunodeficiency Virus (FIV) Integrase.

Monoclonal Designation: In2-18 (Following information updated 4/6/00).

Ig Isotype/subclass plus light chain: IgG1 kappa

Specific antigen reactivity: FIV Integrase. This MAb, and the other 3 anti-integrase MAbs, are new and still under study. It is anticipated that the binding regions of these MAbs will be mapped during 2000.

Negative against Feline Leukemia Virus; Feline Herpes Virus type 1; Feline Coronavirus and Feline Calicivirus.

Properties:

Western blot: positive in reducing gels.

ELISA: positive.

FIV neutralization: Probably negative.

Affinity Chromatography: not known.

Immunofluoresence: not known.

Immunoprecipitation: positive.

Immunohistocytochemistry: not known.

FACS Analysis: not known.

Preparation and supply: SpA purified from tissue culture supernatant and supplied in PBS pH 7.2 with 0.05% sodium azide as preservative. Biotin conjugated MAb also usually available. Pricing: $(US)425.00 per mg SpA purified; $(US)495.00 per mg SpA purified and biotin conjugated. Minimum order 1.0 mg.

In2-18 References: None.

Other related anti-Integrase MAbs available:

In2-1

In2-13

In2-16